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21th ATP to Regulation (EC) No 1272/2008 (CLP Regulation) published

21st Adaptation to technical and scientific progress (21st ATP) to Regulation (EC) No 1272/2008 (CLP) has been published in the Official Journal of the European Union on 5th of January 2024.

After the draft regulation has been circulating between different EU agencies and committees for quite some time, it is now official: The 21. ATP has officially been published and shall apply from 1st September 2025. It can however be used before that date – that is from 25th January 2024. That means your suppliers might start changing the labelling and classification of certain substances very soon!

Quick overview in numbers:

- 27 new entries with an index number,
- 24 existing index number entries are replaced.

What are some most important entries that may affect the most products:

Substance CAS number New harmonized classification
cinnamaldehyde (with isomer) 104-55-2
Skin Sens. 1; H317: C ≥ 0,01 %
nonylphenol, branched and linear, ethoxylated* multiple CAS numbers Aquatic Acute 1; H400
Aquatic Chronic 1; H410; M = 10
benzyl alcohol 100-51-6 Acute Tox. 4; H302
Eye Irrit. 2; H319
Skin Sens. 1B; H317
lead massive:[particle diameter ≥ 1 mm] 7439-92-1 Repr. 1A; H360FD
Lact.; H362
Aquatic Chronic 1; H410; M = 10

*nonylphenol, branched and linear, ethoxylated (with average molecular weight ≤ 1 540 g/mol) [includes ortho-, meta-, para- isomers or any combination thereof]

If you need assistance with understanding what this means for your products and their labelling just write me an e-mail and I will be more than happy to help.

Information on this blog is prepared with utmost care, but it is not about (chemical) consulting, and the provider does not assume any responsibility or liability for the correctness, accuracy and up-to-dateness of published content. If you need advice for a specific case, you can write to us at
SDS UFI / PCN | January 5, 2024

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