
23rd Adaptation to technical and scientific progress (23rd ATP) to Regulation (EC) No 1272/2008 (CLP) has been published in the Official Journal of the European Union on 20 June 2025:
“Commission Delegated Regulation (EU) 2025/1222 of 2 April 2025 amending Regulation (EC) No 1272/2008 of the European Parliament and of the Council as regards the harmonised classification and labelling of certain substances”
It brings changes to the classification and labelling of some existing harmonized substances and adds new harmonized substances in Part 3 of Annex VI.
Quick overview in numbers:
- 22 new entries with an index number,
- 10 existing index number entries are replaced.
The 23rd ATP shall apply from 1 February 2027.
However, suppliers may classify, label and package substances and mixtures in accordance with Regulation (EC) No 1272/2008 as amended by this Regulation from the date of entry into force of this Regulation (10 July 2025).
If you need assistance with understanding the requirements this ATP sets out, we are available and glad to help you.





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